Variant Scanning Of Human Tumors

Gene	Tissue	Fixation	# Samp	Amplicon			Dye	Inst	Sensitivity		Specificity		Min % Det	Title	Author	Year	Link	Email
					Length				Sensitivity		Specificity
				#	Min	Max			%	#	%	#
	Blood		124	2	56	71	LCGreen Plus	LS						Two single nucleotide polymorphisms on chromosome..	Zhou	2011
														Assessment of Chimerism in Epithelial Cancers in..	Leboeuf	2014
	Oral Cancer, saliva	F	52	2			SYTO 9							Oral Candida colonization in oral cancer patients..	Alnuaimi	2015
	Cell lines		10				SYBR Green	RG						A comparative study of digital PCR and real-time..	Carow,..	2017
IDH1/2 and BRAF	Tumor	FFPE	192	3	90	212	SYTO 9	7500 Fast	100	576				Precise Detection of IDH1/2 and BRAF Hotspot..	Hatae,..	2016
12S-rRNA, 16S-rRNA	Tumor	F	244	3		300	ResoLight	LC480					1	Circulating tumor-derived mutant mitochondrial..	Uzawa,..	2016
8q21 and 8q24	Prostate Cancer	F	574				LCGreen Plus	HR-96						Study of Genetic Variants of 8q21 and 8q24..	Hui	2014
8q24	Prostate	F	289					LS						Association of 8 Loci on Chromosome 8q24 with..	Zhao	2013
8q24	Prostate Cancer	F	265	6	38	50	LCGreen Plus	HR-1 96						Risk loci on chromosome 8q24 are associated with..	Liu	2012
8q24	Prostate Cancer, Blood		405					HR-96						rs10505474 and rs7837328 at 8q24 Cumulatively..	Zhang	2014
ABCA13, ABCC12, ABCC13, and ABCG8	Pancreatic Adenocarcinoma	F	32	1	92	92	EvaGreen	RG					5	Differences in Transcript Levels of ABC..	Mohelnikov..	2013
ABCB1	Breast	F	103	4	181	233	EvaGreen	RG	97.1	400				Detection of frequent ABCB1 polymorphisms by..	Vaclavikov..	2012
ABCC2/MRP2 and ABCB1/ MDR1	Tumor	FFPE	58				EvaGreen	Eco						Polymorphisms of Genes Encoding Multidrug..	Szczyrek,..	2017
ABL1	Blood	cDNA	101	4	221	241	SYBR Green I	RG	98.6	70	100	31	5	High-resolution melt curve analysis: initial..	PolÃ¡kov..	2008
AF4, PLFZ, RAG1, TBXAS1	Lung	FFPE	169	4	100	400	LCGreen Plus	LC480						Pyrosequencing Analysis of EGFR and KRAS..	Stigt	2013
AKAP12	Prostate Cancer	F	78				SYTO 9	RG					0	Quantitative assessment of AKAP12 promoter..	Liu	2011
AKT1	Lung	FFPE	219	1	78	78	SYTO 9 (5 ÂµM)	RG						Detection of the transforming AKT1 mutation E17K..	Do	2008
AKT1	Lung	FFPE	73	1			SYTO 9	RG						Dramatic reduction of sequence artefacts from DNA..	Do	2012
AKT1, ALK, APC, BRAF, CDH1, CTNNB1, EGFR, ERBB2,..	Colorectal Tumor	FFPE	81	26			LCGreen Plus	HR-1	100	81				Targeted Next-Generation Sequencing Validates the..	Ham-Karim,..	2019
ALK and ROS1, RET	Lung Cancer		134	8										Transbronchial Biopsy Needle Rinse Solution Used..	Sakairi	2014
ALPK1	Blood	F	95	27	150	354	ResoLight	LC480						Down-regulated and Commonly mutated ALPK1 in Lung..	Liao,..	2016
APC	Colorectal	F	111	5	174	285	ResoLight	LC480					.01	Mutations Using the Example of the Adenomatous..	Gerecke	2013
APC	Blood	F	133	20			ResoLight	LC480						High-resolution Melting Analysis for Gene..	Chang,..	2016
APC, BMPR1A, BRAF, KRAS, MLH 1, MSH 2, MSH 6,..	Tumor	F	103	148	80	356	ResoLight	LC480						Mutation analysis of 13 driver genes of..	Chang,..	2016
APC, MLH1, MSH2, and MSH6	Colorectal, blood	F	8	2	100	250	ResoLight	LC480						High-Resolution Melting Analyses for Gene..	Obul	2012
APC, MUTYH	Blood		70				Syto 9	7500 Fast	100	70	100	70		Molecular basis of familial adenomatous polyposis..	Araujo,..	2019
APC, TP53, PIK3CA, KRAS, and BRAF	Tumor		103	34	102	289	EvaGreen	LC480						Genetic Alterations in Colorectal Cancer Have..	Chen,..	2015
ARID5B, IKZF1	Blood, Leukemia	F	79	6	81	176	SYBR Green I	LC480	100	474	100	474		High-resolution melting analyses for genetic..	Lin	2013
ASXL1, IDH1, IDH2, and c-CBL	Bone Marrow		175	16	286	384		LC480	100		100			Rapid Screening of ASXL1, IDH1, IDH2, and c-CBL..	Ibáñez	2012
ATP5a1, TP53	Colorectal Cancer		16				LCGreen Plus	HR-1						The putative tumour modifier gene ATP5A1 is not..	Seth	2009
BARD1	Tumor, normal	FFPE	455	3	210	293		LS						Cancer predisposing BARD1 mutations affect exon..	Ratajska,..	2015
bcr-abl	Blood		45	1	220	241	ResoLight	LC480	100	19	100	26	5	High-resolution melting analysis for a reliable..	Doi	2009
bcr-abl	Blood	F	63	1			ResoLight	LC480						Exon 7 Deletion in the bcr-abl Gene Is Frequent..	Gaillard	2010
BCR-ABL1	Leukemia, Blood		1					RG						Clinical activity of ponatinib in one patient..	Ferri	2014
BHMT, MTR, MTHFR, MTHFD1, and MTRR	Cervical Cancer		124	2	190	228		LC480						Folate and choline metabolism gene variants and..	Mostowska	2011
BRAC1, BRAC2	Blood		5900	89	200	540	LCGreen Plus	LC 96						Twenty Years of BRCA1 and BRCA2 Molecular..	Machackova..	2019
BRAF	Melanoma	FFPE	90	2	190	250	SYBR Green I	HR-1	100	43	97.1	137		Human malignant melanoma: detection of BRAF- and..	Willmore-P..	2005
BRAF	Colon	F	116	2	190	250	SYTO 9 (1.5 Âµm)	RG	100	11			5	High-resolution melting analysis for rapid..	Simi	2008
BRAF	Colon	FFPE	29				SYTO 9	HR-1						Concomitant mutations and splice variants in KRAS..	Seth	2009
BRAF	Colon	FFPE	73	2	147	238	ResoLight	LC480	100	13			1	Evaluation of High-Resolution Melting Analysis as..	Pichler	2009
BRAF	Melanoma	FFPE	230	1	107	107		LC480	97.3	109	100	112	3.5	Tumor Homogeneity between Primary and Metastatic..	Boursault	2013
BRAF	Lung	F, FFPE, MFPE	2001	3	67	74	LCGreen Plus	LS					1.6	Clinicopathological features of nonsmall cell..	Kinno	2013
BRAF	Melanoma	FFPE	91	1	88	88	SYTO 9	LC480					1.7	A multisite blinded study for the detection of..	Richter	2013
BRAF	WBC		28	1			LCGreen Plus	RG					2.5	Absence of BRAF exon 15 mutations in multiple..	Hatzimicha..	2013
BRAF	Melanoma and pancreatic cancer	F, Cell line	73	3	77	195	ResoLight	LC480						ARMS-PCR for detection of BRAF V600E hotspot..	Machnicki	2013
BRAF	Skin	FFPE	72											Molecular platforms utilized to detect BRAF V600E..	Curry	2012
BRAF	Bone Marrow	F	59	1	88	88	SYTO 9	LC480						Detection of BRAF mutations in patients with..	Blombery	2012
BRAF	Thyroid	F	8	1	147	147	ResoLight	LC480						Detection of BRAF V600E mutation in thyroid..	Nechifor-B..	2012
BRAF	Leukemia, blood/bone marrow	F	48	1	136	136	LCGreen Plus	RG	5-10					High resolution melting analysis for detection of..	Boyd	2011
BRAF	Thyroid Cancer	FFPE	83	1			LCGreen Plus	LC	98.8	82				Allele-Specific PCR with Competitive Probe..	Smith	2011
BRAF	Lung	F	1046					LC480						Clinical Features and Outcome of Patients With..	Marchetti	2011
BRAF	Colorectal Cancer	FFPE	195	1	125	125	SYTO 9		87.5	171	95.7	187	1	Comparison of Allelic Discrimination by dHPLC,..	Carbonell	2011
BRAF	melanoma, lung adenocarcinomas, and colorectal..	FFPE	82	1	163	163	ResoLight	LC480	98	81	100	82	6.6	Comparison of high resolution melting analysis,..	Ihle	2014
BRAF	Colorectal Cancer		13				EvaGreen	CFX96						Application of Genomic Principles to..	Farrell	2014
BRAF	Melanoma	FFPE	113	1			ResoLight	LC480	97	110				Comparative evaluation of the new FDA approved..	Marchant	2014
BRAF	Leukemia, Blood, Bone Marrow	F, FFPE	17	1	136	136	ResoLight	LC480	100	17	100	17		A comparison of high resolution melting,..	So	2014
BRAF	Melanoma and colorectal cancer	FFPE, F	127					LC480						Performance comparison of three BRAF V600E..	Løes	2014
BRAF	Blood, tumor	F	62	2	224	280	S9	Viia7	100	124	91.4		1.25	Non-invasive sensitive detection of KRAS and BRAF..	Mohamed..	2015
BRAF	Blood, bone marrow	FFPE	20	1			EvaGreen	ABI7900						BRAF mutation detection in hairy cell leukaemia..	Thomas,..	2015
BRAF	Tumor	F	648	1			EvaGreen		94.6				5.4	High-Resolution Melting Is a Sensitive,..	Marino,..	2016
BRAF	Tumor	FFPE	59				ResoLight	LC480	87.1		96.4			Detection of BRAF Mutations Using a Fully..	Harlé,..	2016
BRAF	Tumor	FFPE	59				Resolight	LC480	87.1		96.4	58		Comparison of Five Different Assays for the..	Franczak,..	2017
BRAF	Tumor	F	444	1	163	163	Resolight	LC480						Clinicopathological and molecular features of a..	Huss,..	2017
BRAF	Cell lines	FFPE	60	3	55	55	Syto 9	Eco	99.75				0.8	A HRM assay for identification of low level BRAF..	Huebner,..	2017
BRAF	Tumor	FFPE	173				Resolight	cobas 4800						Oncogenic BRAF mutations and p16 expression in..	Mackiewicz..	2017
BRAF	Tumor	FFPE	39	1			Resolight	LC480	94	37	95	37	.1	Rapid BRAF mutation tests in patients with..	Bisschop,..	2018
BRAF	Papillary thyroid carcinoma		19	1					100	9	100	16		Morphological features predictive for BRAF(V600E)..	Nechifor-B..	2018
BRAF	Thyroid tumor	FFPE	27	2	109	137	SYBR	LC480						Evaluation of a DNA Extraction and Purification..	Nechifor-B..	2019
BRAF and EGFR	Tumor, normal	F, FFPE	10				SYBR Green I	HR-1						Frequent BRAF or EGFR Mutations in Ciliated..	Kamata,..	2016
BRAF and KRAS	Lung	FFPE	195	7	75	163			98.75	1348				KRAS and BRAF mutation analysis in routine..	Heideman	2012
BRAF and KRAS	Tumor		143											Prognostic value of BRAF and KRAS mutation status..	de Cuba,..	2016
BRAF and MAP2K1	Tumor	FFPE	52	1				LC480	100	52	100	52		Assessment of BRAFV600E mutation in pulmonary..	Pierry,..	2018
BRAF and NRAS	Melanoma	FFPE	31	10	127	204	EvaGreen	RG					2	Identification of biomarkers to distinguish clear..	Yang	2012
BRAF V600E and CTNNB	Tumor	FFPE, F	18	2			Syto 9	7500 Fast						High-resolution melting and immunohistochemical..	Yoshimoto,..	2018
BRAF V600E and PIK3CA	Colorectal	FFPE	182	3			ResoLight	LC480	95					Characteristics and prevalence of KRAS, BRAF, and..	Hsieh	2012
BRAF, EGFR	Thyroid and Lung Tumors	FFPE	55	3	131	183	LCGreen Plus	HR-1					.1	Enrichment and Detection of Rare Alleles by Means..	Zhou	2010
BRAF, GAPDH	Tumor	FFPE	28	2	109	137	SYBR Green I	LC480						Evaluation of a DNA Extraction and Purification..	Nechifor-B..	2019
BRAF, KRAS	Colorectal	FFPE	75	2	167	173	SYTO 9	RG					.01	A New Microarray Substrate for Ultra-Sensitive..	Galbiati	2013
BRAF, KRAS	Colorectal	FFPE	117	1	155	155	SYTO 9	RG					.8	The Use of COLD-PCR and High-Resolution Melting..	Mancini	2010
BRAF, KRAS	Tumor and normal tissue, Cell lines	FFPE	292	5			LCGreen Plus	ABI7500	83.3		98.1			Cancer mutation screening: Comparison of..	Ebili,..	2015
BRAF, NRAS, and KRAS	Thyroid	FFPE	110	3			SYBR Green	LC480	50.5	56	96	106	12.5	Impact of Diff erent Methodologies on the..	Rehfeld	2013
BRAF, NRAS, KIT, and GNAQ/GNA11	Tumor	F, FFPE	57	10	126	228	SYTO 9	RG	100	570				Mutation scanning of BRAF, NRAS, KIT, and..	Lyu, Wu,..	2016
BRAF, PIK3CA	Colorectal	FFPE	317											Pattern of clinically relevant mutations in..	Yanus	2013
BRCA	Breast and Ovarian Cancer		709	2	236	256			100	1418	100	1418		High-resolution melting analysis for rapid..	Kwong	2010
BRCA1	Breast Cancer		95											Non-founder BRCA1 mutations in Russian breast..	Iyevleva	2010
BRCA1	Breast cancer	F, FFPE	217	2	100	157	LCGreen Plus	HR-1	90	195			.5	Mutation scanning of exon 20 of the BRCA1 gene by..	Vorkas	2010
BRCA1	Breast and Ovarian Cancer, blood		550	1			SYTO 9	LC480						First recurrent large genomic rearrangement in..	Rudnicka	2014
BRCA1	Blood, tumor	F	78	12	360	423	SYTO 9	7500 Fast						Screening of exon 11 of BRCA1 gene using the high..	El..	2015
BRCA1	Blood	F	18	26	133	834	EvaGreen	Eco						Screening of the BRCA1 gene in Brazilian patients..	de..	2016
BRCA1	Blood		100	41			EvaGreen	RG						BRCA1 Gene Mutation Screening for the Hereditary..	Mundhofir,..	2016
BRCA1	Blood	F	85	1			Resolight	LC480	97.5	83				High Resolution Melting Analysis is Very Useful..	Minucci,..	2017
BRCA1	Blood	F	102	12	104	155	Resolight	LC480	100	1224			2.5	Competitive PCR-High Resolution Melting Analysis..	Minucci,..	2017
BRCA1 and BRCA2	Breast, ovarian	F	50	132	114	709		RG						BRCA1/2 mutation screening in high-risk breast/..	Berzina	2013
BRCA1 and BRCA2	Breast		136					LC480						Low prevalence of BRCA1 and BRCA2 mutations in..	de Juan..	2012
BRCA1 and BRCA2	Blood		101				ResoLight	LC480						BRCA1 and BRCA2 unclassified variants and..	Cherbal	2012
BRCA1 and BRCA2	Breast and/or ovarian cancer							LS						Screening of 1331 Danish breast and/or ovarian..	Hansen	2011
BRCA1 and BRCA2	Breast and Ovarian Cancer		521					LC480					0	The occurrence of germline BRCA1 and BRCA2..	Stegel	2011
BRCA1 and BRCA2	Breast and Ovarian Cancer, blood		220	85	179	500	LCGreen Plus	HR-1	95	17765	99	18513		New sequence variants in BRCA1 and BRCA2 genes..	Cvok	2008
BRCA1 and BRCA2	Ovarian Cancer, Blood		258					LC480						An Analysis of Polymorphisms Within the Wnt..	Mostowska	2014
BRCA1 and BRCA2	Breast and ovarian cancer	F	268	8	195	319	SYTO 9	StepOnePlus	100	2144	100	2144		High-resolution melting (HRM) assay for the..	Riahi	2014
BRCA1 and BRCA2	Breast and Ovarian Cancer		753	112	136	435	SYTO 9	LC480						Comprehensive BRCA1 and BRCA2 mutational profile..	Janavicius	2014
BRCA1, BRCA2	Breast Cancer	F	651	5			ResoLight	LC480	100	3255	98.3, 98.6	3200, 3209		Identification of BRCA1/2 Founder Mutations in..	Kwong	2012
BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1	Breast and Ovarian Cancer		82											Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1,..	Kuusisto	2011
BRCA1, BRCA2, PALB2 and BRD7	Breast		40	77			EvaGreen	RG					2.5	Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7..	Pern	2012
BRCA1/BRCA2	Blood		792	1				RG						Association of the microRNA-Single Nucleotide..	Upadhyaya,..	2016
BRCA2	Ovarian	F	12	1	208	217		LC480						High-resolution melting analysis coupled with..	Costella,..	2018
BRCA2,WRN, RAG1, LIG4	Blood, lymphoma	F	107	4			LCGreen Plus							Association of follicular lymphoma risk with..	Salagovic	2012
BRIP1	Ovarian and breast cancer		149	16				LC480						Germline mutations in BRIP1 and PALB2 in Jewish..	Catucci	2012
c- RET	Medullary thyroid carcinoma	F	6	11	98	366	LCGreen Plus	RG, LC480, CFX-96						Establishing high resolution melting analysis:..	Benej	2012
c-kit	GIST	FFPE	31	4	170	235	SYBR Green I	HR-1	100	18	100	56		Detection of c-kit-activating mutations in..	Willmore	2004
c-kit	GIST	FFPE	5	4	170	235	SYBR Green I	HR-1	100	4				c-KIT mutation analysis for diagnosis of..	Willmore-P..	2005
c-kit	Melanoma	FFPE	29	4	170	235	SYBR Green I	HR-1						Human malignant melanoma: detection of BRAF- and..	Willmore-P..	2005
c-kit	Seminoma	FFPE	22	2	170	219	SYBR Green I	HR-1	100	7	100	37		Detection of c-kit exons 11- and 17-activating..	Willmore-P..	2006
c-kit	GIST	FFPE	96	4	170	235	SYBR Green I	HR-1						High-Resolution Melting Amplicon Analysis as a..	Holden	2007
c-kit	Blood		69	2	137	219	ResoLight	LC480	100	18	100	18	1	Rapid detection of KIT mutations in core-binding..	Fuster	2009
c-kit	Tumor	FFPE	29	4	170	235	SYBR Green I	HR-1	100	29	100	29	2	Detection of c-kit-activating mutations in..	Willmore	2004
c-kit	Gastrointestinal Stromal Tumors	FFPE	162	1	202	202		LC480					8.3	Gastrointestinal Stromal Tumors With KIT Exon 9..	Kunstlinge..	2013
c-kit	Mucosal		48	6	150	190		CFX96						KIT mutations in Russian patients with mucosal..	Abysheva	2011
c-kit	Mucosal melanoma, GI metastatic melanoma	FFPE	58											KIT genetic alterations in anorectal melanomas	Santi	2014
c-kit	GIST	FFPE		1	135	171	ResoLight	LC480	100	14	100	8		High Resolution Melting Curve Analysis of DNA..	Becságh	2010
c-kit or PDGFRA	Ocular Melanoma	F	75				LCGreen Plus	LS						KIT mutations in ocular melanoma: frequency and..	Wallander	2011
c-kit, MSH2, MLH1	Colorectal Cancer	FFPE	65	130				LC480, LS	90.9, 71.4		100			Microsatellite Instability Detection by..	Janavicius	2010
CASP9	Breast Carcinoma, tumor, normal, blood	F	808				EvaGreen	RG						Transcript expression and genetic variability..	Brynychova..	2017
CDA	Generic Cancer, blood	F	46				ResoLight	LC480						High-resolution melting analysis of sequence..	Raynal	2010
CDH1	Gastric		236	1				LS					.85%	Novel CDH1 germline mutations identified in..	Chen	2013
CDH1	Lobular carcinoma, blood	F	100											Sequence-based detection of mutations in cadherin..	Valente	2014
CDH1	Gastric cancer	F	359	5	209	298	LCGreen Plus	LS						Correlation between SNPs in CDH1 and gastric..	Lin	2015
CDKN2A	Liver	F	30	3	220	394	LCGreen Plus	LS						Genetic and epigenetic characteristics of human..	Taniguchi	2010
CDKN2A, BNIP3L,	Kidney	FFPE	5	2	242	243	ResoLight	LC480						Human De Novo Papillary Renal-Cell Carcinomas in..	Verine	2013
CEBPA	Leukemia, Bone Marrow, Blood		28	6			EvaGreen	RG					4	CEBPA gene mutational status: a complete..	Rázga	2009
CHEK2	Breast Cancer	F	89					LS						Detecting differential allelic expression using..	Nguyen-Dum..	2011
CHEK2	Thyroid Cancer, Blood	F	100	2	94	133	EvaGreen							Lack of CHEK2 Gene Mutations in Differentiated..	Fayaz	2014
CHEK2			443	2			SYTO 9	RG						Rapid Detection Method for the Four Most Common..	Borun,..	2015
CSMD1	Liver	F	68	13			EvaGreen	CFX96	100	34	96.6	29		Insertion/deletion polymorphisms are convenient..	Marchio	2012
CTNNB1	Liver	F	30	1	313	313	LCGreen Plus	LS						Genetic and epigenetic characteristics of human..	Taniguchi	2010
CYP2D6	Blood	F	80				EvaGreen	RG						CYP2D6 Genetic Polymorphisms and Phenotypes in..	Chin,..	2016
DICER, GEMIN4, DROSHA, AGO1	Tumor and normal	F	30				EvaGreen	LC480						Association between SNPs in microRNA machinery..	Song,..	2017
DICER1	Testicular	F	96	4	68	194	LCGreen Plus	LS						DICER1 RNase IIIb domain mutations are infrequent..	Boer	2012
DLA-DRB1.2	Tumor	FFPE	18	2	168	303	EvaGreen	RG						Association between DLA-DRB1.2 allelic diversity..	Vahedi,..	2019
DNMT1, DNMT3A and DNMT3B	Ovarian	F	159	7	83	179		LC480						DNMT1, DNMT3A and DNMT3B gene variants in..	Mostowska	2013
DNMT3A	Bone Marrow	F	104	12			ResoLight	LC480	100	1248	98	1174		Detection of high-frequency and novel DNMT3A..	Singh	2012
DNMT3A	Leukemia, Bone Marrow	F	168	25			LCGreen Plus	LS	98	4116				Recurrent DNMT3A R882 Mutations in Chinese..	Lin	2011
DNMT3A, IDH1, IDH2	Leukemia, Bone Marrow		230	3	170	249	EvaGreen	RG	95.5	659				Comparative examination of various PCR-based..	Berenstein	2014
DNMT3A, NPM1, FLT3	Bone Marrow	F	69	21	151	300	EvaGreen	CFX96	81.3, 99.2, 100	69			10	Investigation of screening method for DNMT3A..	Mizuta,..	2019
DNMT3B	Blood		317	5	55	110	EvaGreen	LC480						Association between DNA Methyltransferases 3B..	Zheng	2013
DPD	Colorectal Cancer, Blood	F	80	1			EvaGreen	LC480					2	The role of IVS14+1 G > A genotype detection in..	Cai	2014
EED	Colorectal	F	292	3			EvaGreen	RG						EED gene polymorphism in patients with colorectal..	Seo	2013
EGFR	Lung	FFPE	39	4	186	248	SYBR Green I	HR-1	97.4	37	100	119		Detection of epidermal growth factor receptor and..	Willmore-P..	2006
EGFR	SCC	FFPE	24	4	186	248	SYBR Green I	HR-1	100	22	100	74		Detection of EGFR- and HER2-activating mutations..	Willmore-P..	2006
EGFR	Lung	Slide	36	2	51	83	SYBR Green I	HR-1	90.5	21	100	49	0.1	Detection of EGFR Mutations in Archived Cytologic..	Nomoto	2006
EGFR	Lung	FFPE	2	2	204	236	LCGreen Plus	HR-1	100	2			12.5	High-Resolution Melting Amplicon Analysis as a..	Holden	2007
EGFR	Lung	FFPE	10	2	51	83	SYBR Green I	HR-1						Epidermal growth factor receptor mutation status..	Fukui	2007
EGFR	Lung	FFPE	157	2	51	83	SYBR Green I	HR-1	91.9	37	100	89		Epidermal Growth Factor Receptor Mutation..	Takano	2007
EGFR	Lung	MFPE	157	2	51	83	SYBR Green I	HR-1	97.3	37	100	95		Epidermal Growth Factor Receptor Mutation..	Takano	2007
EGFR	Lung	slide	157	2	51	83	SYBR Green I	HR-1	87.5	16	100	40		Epidermal Growth Factor Receptor Mutation..	Takano	2007
EGFR	Lung	FFPE	200	5	121	250	SYTO 9 (5 ÂµM)	RG	100	73	92.4	927		High resolution melting analysis for rapid and..	Do	2008
EGFR	Lung	FFPE/slide	330	2	51	83	SYBR Green I	HR-1						EGFR Mutations Predict Survival Benefit From..	Takano	2008
EGFR	Lung	FFPE	11	4	186	248	SYBR Green I	HR-1						Detection of epidermal growth factor receptor..	Smith	2008
EGFR	Lung	FFPE	121	2	51	83	SYBR Green I	HR-1	100	10	96.6	58		Prospective study of the accuracy of EGFR..	Fukui	2008
EGFR	Lung	MFPE	121	2	51	83	SYBR Green I	HR-1	100	18	100	86		Prospective study of the accuracy of EGFR..	Fukui	2008
EGFR	Lung	Slide	121	2	51	83	SYBR Green I	HR-1	100	11	94.9	59		Prospective study of the accuracy of EGFR..	Fukui	2008
EGFR	Lung	FFPE	120	5			ResoLight	LC480	100	45	96	75		High Resolution Melting Analysis for Epidermal..	Jing	2013
EGFR	Lung	FFPE	10								100	10	2.5	EGFR mutation analysis in sputum of lung cancer..	Hubers	2013
EGFR	Lung	FFPE	484	5	121	250	EvaGreen	RG					1.7	Detection of epidermal growth factor receptor..	Yeen	2013
EGFR	Lung Cancer	FFPE	835	2									1	Evaluation of 2-Year Experience With EGFR..	Hlinkova	2013
EGFR	Lung	FFPE, F	78	4	183	236	ResoLight	LC480	91.67	286	100	312	2.5	Direct serum and tissue assay for EGFR mutation..	Hu	2012
EGFR	Lung		248											EGFR exon mutation distribution and outcome in..	de Mello	2012
EGFR	Lung		180					LC480						EGFR mutation heterogeneity and the mixed..	Chen	2012
EGFR	Lung		58											EGFR mutations detection on liquid-based..	Malapelle	2012
EGFR	Breast	F	1695	2	164	182	ResoLight	RG	100	3390	100	3390	5	Lack of EGFR-activating mutations in European..	Jacot	2011
EGFR	Blood		96				EvaGreen	RG						High-resolution melting analysis for the..	Zhao	2011
EGFR	Lung Cancer	F	522	2					100	1044	100	1044	10	Screening for activating EGFR mutations in..	Sriram	2011
EGFR	Lung Cancer		53	2	194	235		LS					1	Rapid and Efficient Detection of EGFR Mutations..	Hlinkova	2011
EGFR	Lung		157	1	92	92	LCGreen Plus	LS						The different clinical significance of EGFR..	Li	2011
EGFR	Lung Cancer	F, MFPE	577											The usefulness of mutation-specific antibodies in..	Kozu	2011
EGFR	Lung Cancer	FFPE	1	2	204	236	LCGreen Plus	HR-1					12.5	The Use of EGFR Exon 19 and 21 Unlabeled DNA..	Willmore-P..	2008
EGFR	Lung Cancer	FFPE	96				SYTO 9	RG						EGFR gene copy number alterations are not a..	Russell	2014
EGFR	Lung Cancer	F	146	1			SYTO 9	StepOnePlus	90	131			.01	Presence of the minor EGFR T790M mutation is..	Hashida	2014
EGFR	Lung Cancer		362											Epidermal Growth Factor Receptor Test Performed..	Bellevicin..	2014
EGFR	Lung Cancer	FFPE	36				LCGreen Plus	LC480						Detection of EGFR mutation in supernatant, cell..	Lin	2014
EGFR	Tumor	FFPE	330	6				Cobas z480						Antitumoral activity of tyrosine kinase..	Oyaert,..	2015
EGFR	Tumor	FFPE	103				LCGreen Plus							An epidermal growth factor receptor exon 19..	Lu, Li,..	2016
EGFR	Tumor		206				LCGreen Plus	Veriti						Evaluation of epidermal growth factor receptor..	Jain,..	2016
EGFR	Blood	F	6858				ResoLight	LC480 II						Real-time PCR assay with high resolution melting..	Xia,..	2016
EGFR	Tumor	FFPE	123	4	183	238	Resolight	Cobas Z 480						Detection of EGFR mutations in patients with..	Martínez-..	2017
EGFR	Blood/Plasma	F	48	2	290	302		ABI 7500	100	96	100	96	1	Detection of EGFR mutation in plasma using..	Li, Yang,..	2017
EGFR and K-ras	Anal	FFPE	89	1			LCGreen Plus	HR-96						EGFR and K-ras gene mutation status in squamous..	Paliga	2012
EGFR and K-ras	Pancreatic Cancer													Schedule-dependent cytotoxic synergism of..	Wang	2011
EGFR and K-ras	Lung Cancer	F	2											Sequence-Dependent Antiproliferative Effects of..	Chen	2014
EGFR and KRAS	Lung Cancer		108	3	142	190	ResoLight	LC480						Detection of EGFR and KRAS mutations on..	Fassina	2009
EGFR and KRAS	Lung Cancer	FFPE	74										5	A Multicenter Blinded Study Evaluating EGFR and..	Beau-Falle..	2014
EGFR and KRAS	Lung Cancer	FFPE	100	1			SYTO 9	RG						The Clinical Relevance of Pathologic Subtypes in..	Clay	2014
EGFR and KRAS	Lung Cancer	F, FFPE	150	4			LCGreen Plus	LC480	99	594	100	600	1	Snapback Primer Mediated Clamping PCR for..	Sun	2014
EGFR and KRAS	Head and neck cancer	FFPE	52	1	178	178	YOPRO	LC480						Mutation analysis of genes in the EGFR pathway in..	Boeckx	2014
EGFR and KRAS	Tumor	FFPE	178	1	152	152	SYTO 9	RG						Associations between the IASLC/ATS/ERS lung..	Clay,..	2016
EGFR, K-ras	Lung							LC480						Sequence-dependent effect of docetaxel with..	Zhang	2011
EGFR, KRAS	Gastric Cancer		58	3			LCGreen Plus	LS						Epidermal growth factor receptor mutation in..	Liu	2011
EGFR, KRAS	Tumor	FFPE	1472				SYTO 9	RG	95		100	1239	5-7.5	Determination of EGFR and KRAS mutational status..	Papadopoul..	2015
EGFR, KRAS	Tumor	FFPE	143	1	152	152								EGFR and KRAS mutations do not enrich for the..	Clay,..	2017
EGFR, KRAS and BRAF	Lung Cancer			6			LCGreen Plus							The reverse effect of X-ray irradiation on..	Wang	2014
EGFR, KRAS, BRAF and PIK3CA		FFPE	45	2									10	Performance of amplicon-based next generation DNA..	Sie	2014
EGFR, KRAS, BRAF and TP53	Lung Cancer	FFPE	29	1	143	143								Mapping of actionable mutations to histological..	Wright	2014
EGFR, KRAS, PIK3CA and PTEN	Esophagus Cancer	FFPE	38	6				LS						High-incidence of PTEN mutations in Chinese..	Zhang	2014
EMSY	Prostate Cancer, Blood	F	2485											Identification of an aggressive prostate cancer..	Nurminen	2011
ERBB2	Lung	FFPE	39	2	214	252	SYBR Green I	HR-1	100	1	98.7	77		Detection of epidermal growth factor receptor and..	Willmore-P..	2006
ERT-CLPTM1L	Lung	FFPE	492	1			LCGreen Plus	HR-1						The genetic variant rs401681C/T is associated..	Wang	2013
FAM134B	Tumor, Normal	F, FFPE	102				EvaGreen	RG						Identification of Novel FAM134B (JK1) Mutations..	Haque,..	2016
FGFR1	Tumor	FFPE, F	37	4										Droplet digital PCR is a powerful technique to..	Fina,..	2017
FGFR2	Endometrial Carcinoma		43	2			LCGreen Plus	HR-1						Utilization of Unlabeled Probes for the Detection..	Liu	2011
FLT3	Blood / Bone marrow		62	1	328	328	SYBR Green I	HR-1	100	13	100	49	20	High-resolution melting analysis for detection of..	Vaughn	2004
FLT3	Bone marrow		44	1	326	326	ResoLight	LC480						Detection of NPM1 exon 12 mutations and FLT3..	Tan	2008
FLT3	Leukemia	F	121	1			SYTO 9	LC480, RG						Rapid detection of FLT3 exon 20 tyrosine kinase..	Tan	2012
FLT3	Leukemia, Bone Marrow, Blood	F	120	2			ResoLight	LC480						Fms-Like Tyrosine Kinase 3 Mutations in Childhood..	Karabacak	2010
FOXP4	Blood		916				LCGreen Plus	HR-1 96						Association of FOXP4 Gene with Prostate Cancer..	Liu, Shi,..	2015
GEMIN 4	Blood, prostate cancer	F	300	7			EvaGreen	LC480						Genetic variants in the microRNA machinery gene..	Liu	2012
GFR2	Tumor	F	72	6	169	267	Resolight	LC480						Rapid Identification of FGFR2 Gene Mutations in..	Lin, Er,..	2015
GNAS	Pancreas	F	78	1			LCGreen Plus	LS	64.1	50			0.1	Mutant GNAS detected in duodenal collections of..	Kanda	2013
GPR126, PIK3CA	Bladder	F	103	8	86	274								High Prevalence of a Hotspot of Noncoding Somatic..	Garinet,..	2018
GPR30/GPER-1	Breast		30	4	211	505	EvaGreen, LCGreen Plus, ResoLight, SYTO 9	RG						Optimizing high-resolution melting analysis for..	Aihara	2012
H2AFX	Blood, lymphoma, breast cancer	F	573					RG						H2AFX Polymorphisms Are Associated with Decreased..	Jin	2011
H3F3A, H3F3B, IDH1 and IDH2	Tumor	FFPE, F	170	4	56	137	Resolight	LC 480 II						H3F3 mutation status of giant cell tumors of the..	Kervarrec,..	2017
HER2, BRAF, EGFR, and KRAS	Lung Cancer	F	1275	1										HER2 gene mutations in non-small cell lung..	Suzuki	2015
hMLH1	Lung	F, FFPE	181	3				LS						Expression of the Mismatch Repair Gene hMLH1 Is..	Li	2013
HNF1B, MSMB, CTBP2, JAZF1	Prostate Cancer, Blood	F	124	4	50	67	LCGreen Plus	HR-1						Association between single nucleotide..	Zhou	2011
hOGG1	Breast	F	630	1	200	200	LCGreen Plus	LS						Genetic polymorphism in hOGG1 is associated with..	Xie	2013
hOGG1	Colorectal Cancer, Blood	F	622	2	203	255	LCGreen Plus	LS						The hOGG1 gene 5'-UTR variant c.-53G>C..	Liu	2011
IDH	Tumor	FFPE	93	2	106	118	Syto 9	QuantStudio 5						A surgical strategy for lower grade gliomas using..	Koriyama,..	2018
IDH1	Bone marrow, Leukemia	F	110	1	76	76	LCGreen Plus	LS	95	105				Rapid and reliable detection of IDH1 R132..	Lin	2011
IDH1	Brain tumor	F	10	2	129	172	ResoLight	LC480						COLD PCR HRM: A Highly Sensitive Detection Method..	Boisselier	2010
IDH1	Tumor	FFPE	51	1			EvaGreen	RG						Comparative study of IDH1 mutations in gliomas by..	Li,..	2015
IDH1	Tumor	FFPE	213	3	117	118		LC480						IDH-Mutation Is a Weak Predictor of Long- Term..	Amelot,..	2015
IDH1 and IDH2	Leukemia and oral cancer tissue	F	121	3			ResoLight	LC480						Isocitrate dehydrogenase mutation hot spots in..	Tang	2012
IDH1 and IDH2	Leukemia, bone marrow	F	146	2	250	324	ResoLight	LC480	96	280				Diagnostic testing for IDH1 and IDH2 variants in..	Patel	2011
IDH1 and IDH2	Leukemia, Bone Marrow, Blood		168	3			SYTO 9	ABI 7500						Rapid identification of IDH1 and IDH2 mutations..	Noordermee..	2011
IDH1 or IDH2	Bone Marrow		422	3	62	90	LCGreen Plus	LS	98	1241				IDH1 and IDH2 mutation analysis in Chinese..	Lin	2012
IDH1, IDH2	Blood, bone marrow	F	88	2			ResoLight	LC480						Minimal Residual Disease assessment of IDH1/2..	Abdelhamid..	2016
IDH1, IDH2, BRAF, H3F3A, TERT	Tumor, Normal	F	274	5	90	378	SYTO 9	7500 Fast						A comprehensive analysis identifies BRAF hotspot..	Hatae,..	2017
IDH1, IDH2, H3F3A	Tumor	F	400	3	90	102	Syto 9	7500 Fast						Reclassification of 400 consecutive glioma cases..	Akagi,..	2018
IDH2	T-Cell Lymphoma	FFPE	42	1	156	156	Resolight	StepOnePlus	42					Multiple Ways to Detect IDH2 Mutations in..	Dupuy,..	2018
IgH	Lymph node	FFPE	26	7	100	170	SYBR Green ER	LC480	na	na	na		7	Detection of monoimmunoglobin heavy chain gene..	Kummalue	2010
IGH@	Not Specified		20	1	Variable		SYBR Green I	HR-1	100	10	100	10		Rapid and high-resolution detection of IgH gene..	Uemura	2007
IKZF1	Blood, Bone marrow	F	242	11	262	399								IKZF1 deletions predict a poor prognosis in..	Yang	2011
IL-18	Prostate	F	375											Effect of IL-18 gene promoter polymorphisms on..	Liu	2013
ITGA3, ITGA6, ITGB3, ITGB4, ITGB5,	Gastric Cancer, Blood	F	1000				EvaGreen	LC480						Association between polymorphisms of..	Song	2015
ITGAv, ITGB5, ITGA6, ITGB3, ITGA3	Prostate	F	347	5			EvaGreen	LC480						Genetic variants in the integrin gene predicted..	Liu	2012
ITGB5	Bladder Cancer, Blood	F	317											Association between polymorphisms in the integrin..	Liu	2014
JAK2	Blood		50	1	126	126	LCGreen Plus	RG	100	4	100	46	5-20	Rapid identification of JAK2 exon 12 mutations..	Jones	2008
JAK2	Blood		33	1	155	155	ResoLight	LC480	100	11	100	22	5	Detection of the JAK2 V617F missense mutation by..	Er	2009
JAK2	Blood		70	1	280	280	ResoLight	LC480	100	3	100	67	0.5	High resolution melting analysis for JAK2 Exon 14..	Rapado	2009
JAK2	Bone Marrow	F, FFPE	104	5	50	136	LCGreen Plus	LS-32	99.6					Detection of JAK2 mutations in paraffi n marrow..	Nussenzvei..	2012
JAK2	Bone Marrow		16	1			ResoLight	LC Nano	95	15			0.2	Advantages of the quenching probe method over..	Ono	2012
JAK2	Leukemia, bone marrow	F	223				LCGreen Plus	LS	95					Detection of the JAK2 Mutation in..	Cao	2011
JAK2	Leukemia, Bone Marrow	F	105				LCGreen Plus	LS	100	40	100	57		Rapid detection of JAK2 V617F mutation using..	Qian	2010
JAK2	Bone Marrow	FFPE	12	1	100	100	LCGreen Plus	LS-32						Deparaffinization With Mineral Oil: A Simple..	Heikal	2014
JAK2	Blood, bone marrow	F	177	1			ResoLight	LC						Simultaneous screening for JAK2 and calreticulin..	Matsumoto,..	2016
JAK3	Lymphoma	F	65	2	64	83	EvaGreen	CFX96						Janus kinase 3-activating mutations identified in..	Koo	2012
K-RAS	Ovarian and colon cancer	FFPE	40	1	55	55	SYBR Green I	CFX96						Mutation Scanning of Short Amplicons:..	Botezatu	2012
K-ras	Pancreatic Cancer	FF	50	2	59	163	ResoLight	LC480	97	97			10	Differential High-Resolution Melting Analysis for..	Zhang	2011
K-ras	Lung Cancer, Colorectal Cancer	FFPE	98	1	117	117	LCGreen Plus	LC480	98.75					A fast, sensitive and accurate high resolution..	Kramer	2009
K-RAS and B-RAF	Esophageal	FFPE	44	4	121	225		LC480						pERK activation in esophageal carcinomas:..	Tasioudi	2012
KCNQ1	Heart, liver	FFPE, F	8	18	107	300	ResoLight	LC480						Detection of genetic variation in KCNQ1 gene by..	Farrugia	2012
KIT	Bone Marrow		127				ResoLight	LC480					10	High-Resolution Melt Curve Analysis in Cancer..	Mehrotra,..	2016
KIT	Bone Marrow	F	69	1	219	219	Syto 9	ABI 7500						Detection of KIT mutations in core binding factor..	Badr,..	2018
KLK3	Prostate		266					LS						Susceptibility Loci Associations with Prostate..	Wang	2013
KLLN	Breast		556	4										Analysis of KLLN as a high-penetrance breast..	Thompson	2012
KRAS	Colon	FFPE	118	8				LC480	100	118	65.7	118	8	KRAS mut.: Comparison of testing methods and..	Franklin	2010
KRAS	Tumor	F	68	2	166	166		LS	100	76	96	89	2	Sensitive and Specitifc KRAS somatic mutation..	Eijk	2010
KRAS	Lung	FFPE	30	2	92	92	SYTO 9 (5 ÂµM)	RG	100	9	100	21	5	High resolution melting analysis for the rapid..	Krypuy	2006
KRAS	Lung	FFPE	30	2	189	189	SYTO 9 (5 ÂµM)	RG	100	9	100	21	10	High resolution melting analysis for the rapid..	Krypuy	2006
KRAS	Lung	FFPE	200	1	92	92	SYTO 9 (5 ÂµM)	RG						High resolution melting analysis for rapid and..	Do	2008
KRAS	Colon	F	116	1	167	167	SYTO 9 (1.5 Âµm)	RG					5	High-resolution melting analysis for rapid..	Simi	2008
KRAS	Liver	FFPE	29				SYTO 9	HR-1	100	14				Concomitant mutations and splice variants in KRAS..	Seth	2009
KRAS	Colorectal	FFPE	212	1			LCGreen Plus	LC480						High resolution melting analysis of KRAS, BRAF..	Guedes	2013
KRAS	Colorectal	FFPE	647	3			ResoLight	LC480	99	633	100	635	5	Optimization of routine KRAS mutation PCR-based..	Chretien	2013
KRAS	Colon Cancer	FFPE	40	1	117	117	LCGreen Plus	LC480					2.5	KRAS mutation analysis on low percentage of colon..	Dijkstra	2013
KRAS	colorectal carcinomas	FFPE	156				ResoLight	LC480					10	Comparison of COBAS 4800 KRAS, TaqMan PCR and..	Harlé	2013
KRAS	Lung	F	114	1			LCGreen Plus	LC480	77	14	98	94	5	A comparison of Direct sequencing,..	Jancik	2012
KRAS	Rectal adenocarcinoma	FFPE	71				ResoLight	RG, LC480						KRAS genotyping in rectal adenocarcinoma..	Boissie`re..	2012
KRAS		FFPE		2			SYTO 9	Viia 7					0.5	Improving the limit of detection for Sanger..	Davidson	2012
KRAS	Colorectal	FFPE	50	1	114	114	SYTO 9	ABI 7500					3	KRAS mutation detection by high-resolution..	Malapelle	2012
KRAS	Pancreatic	FFPE	49	1	166	166	SYTO 9	RG	97	48			3	Unlabeled-probe high-resolution melting to detect..	Guo	2012
KRAS	Colorectal Cancer	FFPE	372	1	92	92	LCGreen Plus	LC480	97.5	89.7				Comparison of methodologies for KRAS mutation..	Pinto	2011
KRAS	Colorectal Cancer	FFPE, F	131	1	84	84	ResoLight	RG, LC480						KRAS Mutation Detection in Paired Frozen and..	Solassol	2011
KRAS	Lung Cancer	F	12	3	65	160	LCGreen Plus	HR-96	99.7					Rapid and Sensitive Detection of KRAS Mutation..	Song	2011
KRAS	Colorectal Cancer	FFPE	164	1	114	114	HR-1	LS						KRAS mutation detection and prognostic potential..	Deschoolme..	2010
KRAS	Colorectal Cancer	FFPE	61	1	56	56	SYTO 9	RG					.1	Increased Sensitivity of KRAS Mutation Detection..	Kristensen	2010
KRAS	Colorectal Cancer	F	60				ResoLight	LC480	95	57			5	Comparison of two different screening methods for..	Er	2010
KRAS	Colon Cancer	FFPE	10	1	154	154	LCGreen Plus	LS					.1	Detection of Low-Level KRAS Mutations Using..	Oh	2010
KRAS	Colon cancer	FFPE	60	1			LCGreen Plus	RG	100	60	98	59	1	LNA-based PCR clamping enrichment assay for the..	Efrati	2010
KRAS	Colorectal Cancer	FFPE	48	1	170	170	ResoLight	LC480						KRAS mutation detection in Tunisian sporadic..	Karim	2010
KRAS	Gastric Adenocarcinomas	F	52	1	167	167	LCGreen Plus	HR-96						Mutation detection of KRAS by high-resolution..	Liu	2009
KRAS	Colorectal Cancer	FFPE	100	1	170	170	ResoLight	LC480					5	Detection of KRAS mutations in colorectal cancer..	Ma	2009
KRAS	Lung Cancer	F	103	1	167	167	LCGreen Plus	LS					2.5	The status of KRAS mutations in patients with..	Li	2009
KRAS	Colorectal Cancer	F, FFPE	154	2	80	92	SYTO 9	RG, LC480						A multicenter blinded study to evaluate KRAS..	Whitehall	2009
KRAS	Colorectal Cancer													Electrochemical biosensor based on functional..	Wang	2014
KRAS	Lung Cancer	FFPE	106					RG						Epidermal growth factor receptor and KRAS..	Fakhruddin	2014
KRAS	Pancreatic Adenocarcinoma	F	36	1	166	166	SYTO 9	RG	99.9					Co-amplification at Lower..	Wu	2014
KRAS	Biopsy	FFPE	55	1	170	170		LC480 II	100					Comparison of High-Resolution Melting Analysis,..	Zhang,..	2015
KRAS	Tumor	FFPE	119	1	92	92	LCGreen Plus	LS						Impact of KRAS mutation on response and outcome..	Yagishita,..	2015
KRAS	Tumor	FFPE	102	1	92	92	LCGreen Plus	LS	100	102	100	102	1	KRAS Mutations in Patients with Colorectal Cancer..	Akiyoshi,..	2013
KRAS	Tumor	F	127	3				LS-96						Concomitance of P-gp/LRP Expression with EGFR..	Wei, Lu,..	2016
KRAS	Tumor, normal, blood	FFPE	93				SYTO 9	ABI 7500 Fast	95	88	89	83	3	Circulating tumor DNA outperforms circulating..	Freidin,..	2015
KRAS	Tumor	FFPE	79					LC480						Rare discrepancies in a driver gene alteration..	Zhong,..	2015
KRAS	Plasmid	FFPE	2	1	45	45	ResoLight	LC Nano	95					Locked nucleic acid probe enhances Sanger..	Ishige,..	2016
KRAS	Blood	FFPE	35	2				LC480	83	58	71.4	50	5	Droplet digital PCR of circulating tumor cells..	Denis,..	2016
KRAS	Blood, tumor	FFPE	61	1	92	92	SYTO 9	RG					12.5	A rational two-step approach to KRAS mutation..	Mack,..	2016
KRAS								LC480						Screening of KRAS Mutation in Pre- and..	Trujillo-A..	2016
KRAS	Metastatic colorectal cancer	FFPE	112	12			Syto 9	RG	92	1238	89	1192		Impact of fixation artifacts and threshold..	Pérez-Bá..	2017
KRAS	Colorectal Tumor	Fresh Frozen	47	1			Syto 9	StepOnePlus	83.3	47	96.6	47		High-resolution melting for detecting KRAS..	Miranda,..	2019
KRAS and BRAF	Colorectal	FFPE	190	1	250	250	ResoLight	LC480					1	KRAS and BRAF mutations in Serbian patients with..	Jakovljevi..	2012
KRAS and BRAF	Colorectal adenocarcinoma	FFPE	126	2	154	189	ResoLight	LC480					1	Concordance in KRAS and BRAF mutations in..	Krol	2012
KRAS and BRAF	Colorectal	FFPE	110	5	151	170	ResoLight	LC480						A Multiplex SNaPshot Assay as a Rapid Method for..	Magnin	2011
KRAS and BRAF			205											Bevacizumab plus XELOX as first-line treatment of..	Antonuzzo,..	2015
KRAS and BRAF	Tumor	F	1000	1			LCGreen Plus	LC480 II						Mutation Analysis of KRAS and BRAF Genes in..	Koochak,..	2016
KRAS and BRAF	Tumor	FFPE, F	242	1			EvaGreen	LC 480 II	100	242	100	242		Sensitive High-Resolution Melting Analysis for..	Karbalaie..	2016
KRAS and EGFR	lung and colon carcinomas	FFPE	18											Next-generation sequencing analysis of lung and..	Chevrier	2014
KRAS and EGFR	Tumor	FFPE	25					RG, LC480 II						Comparison of Next-Generation Sequencing and..	Hinrichs	2015
KRAS and GNAS	Pancreatic duct fluid	F	36	2			LCGreen Plus	LS						Mutant KRAS and GNAS DNA Concentrations in..	Sadakari	2014
KRAS and GNAS	Pancreatic cancer, pancreatic juice	F	272	3	119	340	LCGreen Plus	LS						KRAS and GNAS Mutations in Pancreatic Juice..	Eshleman	2015
KRAS and GNAS	Pancreatic duct	FFPE	70	2	119	188	EvaGreen							Assessment of clonality of multisegmental main..	Tamura	2014
KRAS and PIK3CA	Tumor	F, FFPE	156	4			LCGreen Plus							Identification of KRAS and PIK3CA but not BRAF..	Lu, Wei,..	2015
KRAS, AKT1, PIK3CA, and BRAF	Various	FFPE	7	15	100	186	ResoLight	LC480					3.1	High-Resolution Melting Analysis as a Sensitive..	Ney	2012
KRAS, APC, BRAF, TP53	Stool, tumor	F	27	21	100	350	LCGreen Plus	LS			92	522	.1	High detection rates of colorectal neoplasia by..	Zou,..	2009
KRAS, BRAF	Colorectal	FFPE	60	1				PE 9700					1	Duplex reverse-hybridization assay for the..	Buxhofer-A..	2013
KRAS, BRAF	Colorectal Cancer	FFPE	22	1				HR-1					1.5	Comparative analysis of pyrosequencing and..	Ibrahem	2010
KRAS, BRAF	Colorectal Tumor	FFPE	5546				EvaGreen	LC480, RG						Demographic trends and KRAS/BRAF mutations in..	Fu,..	2019
KRAS, BRAF and EGFR	Colorectal or lung cancer	FFPE	120	5	128	250	ResoLight	LC480					2.5	Clinical pharmacogenomic testing of KRAS, BRAF..	Borràs	2011
KRAS, BRAF and PIK3CA	Colorectal	FFPE	209	4			SYTO 9	RG					5	Survey of KRAS, BRAF and PIK3CA mutational status..	Bozzao	2012
KRAS, BRAF and PIK3CA	Colon Cancer	FFPE	130				ResoLight	LC480						Predictive and prognostic factors in the complex..	László	2010
KRAS, BRAF, NRAS	Colorectal liver metastases	PE	3590					LC480						Colorectal liver metastases are more often super..	Allard	2014
KRAS, BRAF, NRAS	Colorectal Tumor	FFPE	157				Resolight	LC480						Microsatellite Instability in Greek Colorectal..	Katafygiot..	2019
KRAS, BRAF, PIK3CA, EGFR	Colon	FFPE	58	3			SYTO 9	RG					1	Competitive Amplification of Differentially..	Kristensen	2012
KRAS, BRAF, PIK3CA, TP53	Colorectal cancer	FFPE	30	13			LCGreen Plus	ABI 7500						The utility of diagnostic biopsy specimens for..	Fadhil	2012
KRAS, EGFR	Lung Cancer	FFPE	53	2				RG						From clinical trials to clinical practice:..	Mazzoni	2011
KRAS, EGFR	Lung Cancer	FFPE	2	2	189	250	SYTO 9	RG						Limited copy number - high resolution melting..	Do	2009
KRAS, HRAS, NRAS, and BRAF	Thyroid		252	5	140	173	SYTO 9	RG					5	A High-Resolution Melting Protocol for Rapid and..	Mancini	2012
KRAS, NRAS	Tumor	F	87	2	293	517	EvaGreen	LC 96						Common KRAS and NRAS gene mutations in sporadic..	Hamzehzade..	2018
KRAS, NRAS and BRAF	Colorectal Cancer	FFPE	2425	7	92	155	SYTO 9	RG	95	16975				KRAS, NRAS and BRAF mutations in Greek and..	Negru	2014
KRAS, NRAS, and BRAF	Colorectal Cancer	FFPE	93	7	92	150	ResoLight	LC480						High-throughput screening of extended RAS..	Ishige	2014
KRAS, NRAS, BRAF, PIK3CA	Tumor	FFPE, F	50				ResoLight	LC480						Beside P53 and PTEN: Identification of molecular..	Chen,..	2016
KRAS, NRAS, BRAF, PIK3CA	Colorectal Tumor	FFPE	102	2				Eco						Analysis of KRAS, NRAS, BRAF, and PIK3CA..	Krawczyk,..	2018
KRAS, NRAS, HRAS, BRAF, PIK3CA	Tumor	FFPE	149	12	<200	<200	LCGreen Plus	LC480						GNAS but Not Extended RAS Mutations Spectrum are..	Gaujoux,..	2019
KRAS, NRAS, HRAS, BRAF, PIK3CA, MET, TP53 and..	Tumor	FFPE	148	23	86	274	LCGreen Plus	LC480						Mutational analysis of anal cancers demonstrates..	Cacheux,..	2016
KRAS, p16/CDKN2A, GNAS, or BRAF.	Tumor, normal		169	3	119	340	LCGreen Plus	LS					5	Presence of Somatic Mutations in Most Early-Stage..	Kanda,..	2012
KRAS, PIK3CA	Tumor	FFPE	50	10	100	400	LCGreen Plus	HR-1	100	50	100	50	10	QMC PCR follwed by HRM	Fadhil	2010
KRAS, TP53	Colorectal, Lung	Cell lines		50	120	190		HR96					.05	Differential strand separation at critical..	Guha	2013
KRAS, TP53, APC, PICK3CA, BRAF	Colorectal Tumor		103	5			Resolight, Evagreen	LC480						Metabolic Imaging Phenotype Using Radiomics of [..	Chen,..	2019
KRAS/TP53	Colorectal Cancer	FFPE	175	7	92	186	EvaGreen, ResoLight	RG, LC480	100	1225	100	1225	1	High-Resolution Melting Assay (HRMA) is a Simple..	Li	2012
L265P	Lymphoma	FFPE	120	1	59	59	LCGreen Plus	LS					0	Development of high-resolution melting analysis..	Wang	2013
LOH of PTCH1	Ovarian carcinoma	F	37	24	168	428	LCGreen Plus	HR-1						LOH of PTCH1 region in BCC and ovarian carcinoma:..	Musani	2012
MED12	Tumor	F	338	2	98	290	EvaGreen	LC480						High-Resolution Melting Analysis of MED12..	Wang	2015
MEK1	Tumor	FFPE	175	1			CXR	Eco						Sensitive methods for screening of the MEK1 gene..	Nicos,..	2016
MET	Colorectal Cancer	FFPE	299		250	500	LCGreen Plus	LS						Activating mutation in MET oncogene in familial..	Neklason	2011
MicroRNA genes (10)	Ovary	F	90	20			SYTO 9 (2.5 ÂµM)	LS						Genetic analysis of cancer-implicated MicroRNA in..	Bearfoot	2008
miRNA	Liver Cancer, tumor and blood	FFPE, F	314	4	47	81	LCGreen Plus	LS-32						High-resolution melting analysis reveals genetic..	Qi	2014
MLH1	Colorectal cancer, mucosa, blood	F	104	1			ResoLight	LC480						A novel c. 204 Ile68Met germline variant in exon..	Vodicka	2015
MLH1	Blood	F	467	2	76	244	SYTO 9	RG						Molecular analysis of MLH1 variants in Chinese..	Peng, Xu,..	2016
MMP, TIMP	Bladder	F	241					CFX96						Genetic polymorphisms in matrix..	Wieczorek	2013
MMR	Colorectal	F	18				ResoLight	LC480						Somatic mosaicism and double somatic hits can..	Sourrouill..	2013
MPL	Blood		175	1	107	107	LCGreen Plus	RG	100	9	100	9	11	Clinical utility of routine MPL exon 10 analysis..	Boyd	2010
MPO	Blood		969	1			ResoLight	LC480						Involvement of myeloperoxidase gene polymorphism..	Roszak,..	2016
MRE11A, RAD50, and NBN	Breast Cancer		1313						99		99.2			Rare key functional domain missense substitutions..	Damiola	2014
MSMB, 11p15, 11q13, HNF1B, 17q24, KLK2/KLK3	Blood, Prostate Cancer	F	289	1	45	45	SYBR Green I	TMHR-I 96						Association of Six Susceptibility Loci with..	Zhang	2012
MTHFR	Blood	F	219					LC480						Risk factors for cholangiocarcinoma in high-risk..	Songserm	2012
MTHFR	Liver cancer		219				ResoLight	LC480						MTHFR Polymorphisms and Opisthorchis viverrini..	Songserm	2011
MUTYH	Colorectal	F	38				ResoLight	LC480					2.5	Unexplained polyposis: a challenge for..	Mongin	2012
MUTYH	Colorectal	F	88	2		300	SYTO 9	RG	100	176	100	176		High resolution melting analysis for a rapid..	Tricarico	2011
MUTYH	Melanoma, Blood	F	195	3			ResoLight	LC480						Common genetic variants of MUTYH are not..	Santonocit..	2011
MUTYH	Breast Cancer		287				LCGreen Plus	LS						Deep Sequencing to Reveal New Variants in Pooled..	Out	2009
NAT2	Blood	F	198	3				LC480						Active cigarette smoking and the risk of breast..	Kasajova,..	2016
NCOA3	Breast Cancer		172	1	62	62	SYTO 9	RG						Investigation of the 1758GNC and 2880ANG variants..	Gabrovska	2011
NOTCH1	Blood, Tumor, Normal		695	37	145	1611	EvaGreen	LC480						Somatic Mutations and Genetic Variants of NOTCH1..	Liu,..	2016
NOTCH1	Leukemia, bone marrow		133	2	116	131	EvaGreen	LC480	99	263				High-resolution melting analysis for rapid and..	Xu, Yao,..	2017
NPM1	Bone marrow		44	1	186	186	ResoLight	LC480						Detection of NPM1 exon 12 mutations and FLT3..	Tan	2008
NPM1	Blood	F	337	1	232	232	ResoLight	LC480					2.3	New Quantitative Method to Identify NPM1..	Huet	2013
NPM1			89	1			SYTO 9	RG	95	85				Evaluation of methods for detection of NPM1 gene..	Li	2011
NPM1	Leukemia, Bone Marrow, Blood		70					LC480						Study on NPM1 gene mutations in childhood acute..	Zhou	2010
NRAS	Liver	F	30	1	243	243	LCGreen Plus	LS						Genetic and epigenetic characteristics of human..	Taniguchi	2010
NRAS	Skin	F, FFPE	39	1	113	113	ResoLight	LC480					5	NRAS Mutation Is the Sole Recurrent Somatic..	Charbel	2013
p53	Ovarian	F	110	5			SYTO 9	RG					3.3	The Role of p53 Protein and MMP-2 Tumor/Stromal..	Grelewski	2013
P53	Lung		318	4			ResoLight	LC480						High resolution melting analysis for detecting..	Chen	2011
P53	Merkel cell carcinomas	FFPE	27	1	143	143	EvaGreen	RG						P53 mutation is a rare event in Merkel cell..	Lill	2011
p53	Breast	F	140	4	144	210	ResoLight	LC480	100	560	83	465		Genetic mutations and expression of p53 in..	Mao	2010
p53			24											Detection of p53 Mutations in Circulating DNA of..	García-Fe..	2016
p53, K-ras, BRAF, and EGFR	Pancreatic/biliary duct tumor	FFPE	20	12	169	271	LCGreen Plus	HR-1						Molecular Diagnostic Testing as an Adjunct to..	Willmore-P..	2007
p73	Lung Cancer	F	168	1			SYBR Green I	LC Nano						Association between a p73 Gene Polymorphism and..	Wang	2014
PALB2	Breast		747	4	100	310	SYTO 9	RG						Prevalence of PALB2 mutations in Australasian..	Teo	2013
PALB2	Breast and pancreas cancer		77											Germline PALB2 mutation analysis in..	Stadler	2011
PALB2	Breast Cancer		203	30			EvaGreen	RG						PALB2 mutations in German and Russian patients..	Bogdanova	2011
PALB2	Breast Cancer, Blood		3,924	1			EvaGreen	RG						Prevalence of PALB2 mutation c.509_510delGA in..	Noskowicz	2014
PALB2	Blood	F	47	1	286	286	LCGreen Plus	LS-32						Development of a novel PTT assay for mutation..	Poumpourid..	2016
PALB2	Blood		1378	13			EvaGreen	LC480						Mutation analysis of the PALB2 gene in unselected..	Borecka,..	2016
PALB2, XRCC2	Breast		95	60										Hi-Plex for high-throughput mutation screening:..	Nguyen-Dum..	2013
PARP-1	Cervical		446	1				LC480						Involvement of PARP-1 Val762Ala Polymorphism in..	Roszak	2013
PARR	B-Cell Lymphoma	FFPE	78	7	140	210	EvaGreen	RG					12.5	High resolution melting analysis (HRM) for the..	Henrich,..	2018
PDGFRA	GIST	FFPE	5	2	200	235	SYBR Green I	HR-1	100	1	100	1		c-KIT mutation analysis for diagnosis of..	Willmore-P..	2005
PDGFRA	GIST	FFPE	96	2	200	235	SYBR Green I	HR-1						High-Resolution Melting Amplicon Analysis as a..	Holden	2007
PDGFRA	Gastrointestinal	FFPE	159	2	102	213		LC480	100	318	100	318	6	High-resolution melting analysis is a sensitive..	Kunstlinge..	2013
PIK3CA	Colon	F	116	2	130	135	SYTO 9 (1.5 Âµm)	RG					3	High-resolution melting analysis for rapid..	Simi	2008
PIK3CA	Breast cancer	FFPE	149	2			ResoLight	LC480					.5	Analysis of PIK3CA exon 9 and 20 mutations in..	HARLÉ	2013
PIK3CA	Colorectal	F	426	2			SYTO 9	RG						Oncogenic PIK3CA mutations in colorectal cancers..	Whitehall	2012
PIK3CA	Breast	FFPE	129	4	70	352	LCGreen Plus	HR-1	95	122			1	PIK3CA Hotspot Mutation Scanning by a Novel and..	Vorkas	2010
PIK3CA	Bladder Cancer, Seborrheic Keratosis	F, FFPE	180	2	109	139		LS	90-95				1	A SNaPshot assay for the rapid and simple..	Hurst	2009
PIK3CA	Breast Cancer	F	101	2	96	100	ResoLight	LC480						Detection of PIK3CA Gene Mutations with HRM..	Dirican	2014
PIK3CA	Tumor, normal		42	10	100	400	ResoLight	LC480					3	Particular molecular and ultrastructural aspects..	Mihalcea,..	2015
PIK3CA	Tumor	F	58											Somatic mutation in PIK3CA is a late event in..	Verlaat,..	2015
PIK3CA	Tumor	FFPE	175	2			Chromofy	Eco					1	PIK3CA Mutations Detected in Patients with..	Nico?,..	2016
PIK3CA	Bladder	F	50	4	99	387	EvaGreen	RG						High Resolution Melting Analysis for Rapid..	Ashtiani,..	2018
PIK3CA	Breast	F	40	2			EvaGreen	RG					6.2	A Comparison Between Full-COLD PCR/HRM and PCR..	Ghalamkari..	2018
PIK3CA	Breast	FFPE	46	14	85	155	Resolight	LC480						Comparison of Three Real-Time PCR Assays for the..	Lambert,..	2018
PIK3CA and BRAF	Lung	F	524	12										Identification of enriched driver gene..	An	2012
PIK3CA, AKT1	Tumor, Cell lines	FFPE	44	3			ResoLight	LC480						Immunohistochemical and molecular analysis of..	Tasioudi,..	2015
PIK3CA, AKT1, KRAS, BRAF	Breast	FFPE	57	5	78	144	SYTO 9	RG						PIK3CA mutations are frequently observed in BRCAX..	Deb	2013
PIK3CA, AKT1, PTEN	Tumor	F	75				SYBR Green I	LC480						Mutation of genes of the PI3K/AKT pathway in..	Tserga,..	2016
PIK3CA, BRAF, PTEN	Colorectal	FFPE	572	2			SYTO 9	RG						PIK3CA, BRAF, and PTEN Status and Benefit from..	Karapetis	2013
PIK3CA, ERBB2, KRAS, TP53, EGFR, BRAF, GATA3, and..	Breast, endometrial and ovarian cancers	FFPE	180				LCGreen Plus	LS	88		80			Detection of Somatic Mutations by High-Resolution..	Gonzalez-B..	2011
PIK3CA, ERBB2, KRAS, TP53, EGFR, BRAF, GATA3, and..	Breast, endometrial and ovarian cancers	F	216				LCGreen Plus	LS	97		87			Detection of Somatic Mutations by High-Resolution..	Gonzalez-B..	2011
PIK3CA, KRAS, EGFR, TP53	Tumor	F	24	12	119	300	SYTO 9	StepOne						Detection of oncogenic mutations in cervical..	Wayhelova,..	2016
PIK3CA/PTEN	Tumor	FFPE	18	7	124	299	Syto 9	RG						Pilot investigation of the mutation profile of..	Malentacch..	2018
PLA2G2A, IL-16, NOD2	Bone Marrow	F		3	194	250	ResoLight	LC480						High-resolution melting (HRM) analysis for the..	Lin	2012
PLCE1, C20orf54	Esophageal	F	322	2			SYTO 9	RG						Replication of results of genome-wide association..	Piao	2013
PLEKHS1	Bladder	F	355	1	107	107								PLEKHS1: A new molecular marker predicting risk..	Pignot,..	2019
PPARG, RET	Follicular Thyroid	FFPE	310	1			SYBR Green	LC480						Impact of Molecular Screening for Point Mutations..	Eszlinger	2013
PPP2CA	Breast Cancer		4					RG						Deregulation of the phosphatase, PP2A is a common..	Baldacchin..	2014
PPP3CA and MARK4	Breast, blood	F	182	2	114	74	SYTO 9	RG						Investigation of Two Wnt Signalling Pathway..	Gabrovska	2011
PTEN	Kidney	FFPE	22	4	153	212		LC480	100	21	100	21	4	Loss of PTEN/MMAC1 activity is a rare and late..	Grill	2010
PU.1	Blood	F		1	73	73	CXR	CFX96	100		100		42	Molecular characterisation of murine acute..	Steffen	2013
RAD18, MMP7	Tumor, bowel wall outside the tumor, and all..	FFPE	163	2	85	93	Resolight	LC480						Single nucleotide polymorphisms in genes MACC1,..	Horvat,..	2016
RAD51C	Blood, Breast and Ovarian Cancer	F	192	9	216	379	LCGreen Plus	LS						Mutation screening of RAD51C in high-risk breast..	Lu	2012
RAD51C	Breast and Ovarian Cancer		492	12	155	253	ResoLight	LC480						A HRM-based screening method detects RAD51C..	Romero	2011
RAD51C and RAD51D	Blood		1397	20			EvaGreen	LC480						Mutation Analysis of the RAD51C and RAD51D Genes..	Janatova,..	2015
RAD51D	Breast and Ovarian Cancer, Blood	F	842											About 1% of the breast and ovarian Spanish..	Gutierrez-..	2014
RAD51L1	Breast Cancer		188	16	48	257	ResoLight	LC480						Mutation analysis of RAD51L1 (RAD51B/REC2) in..	Johnson	2011
RAS	Blood	F	504	4	78	95		LS						RAS mutation analysis in a large cohort of..	Yang	2013
RAS, BRAF, TP53	Colorectal	F	165	9			ResoLight	LC480						RAS, BRAF, and TP53 Gene Mutations in Taiwanese..	Chang	2013
RASEF	Melanoma	F	46	16	185	967	LCGreen Plus	LS						Epigenetic regulation identifies RASEF as a..	Maat	2008
RET	Blood, medullary thyroid carcinoma nor multiple..	F	136	1				LS-32					.5	Determination of RET Sequence Variation in an..	Margraf	2012
RET	Medullary thyroid carcinoma		80	2			LCGreen Plus	LC480	100	160	100	160		Rapid Diagnosis of MEN2B Using Unlabeled Probe..	Margraf	2008
RET	Medullary thyroid carcinoma		80	6	114	235	LCGreen Plus	HR-1						Mutation Scanning of the RET Protooncogene Using..	Margraf	2006
RGSL1, RGS16, and RGS8	Breast Cancer		200	51	83	286	ResoLight	LC480			100	10200		High-Resolution Melting Analysis for Mutation..	Wiechec	2011
RNF8, UBC13 and MMS2	Breast		123	19	197	498								Mutation screening of the RNF8, UBC13 and MMS2..	Vuorela	2011
SAO, G701D	Blood		31	2	173	318	Resolight	LC480						Molecular Diagnosis of Solute Carrier Family 4..	Deejai,..	2018
SF3B1	Blood	F	275	3	51	119	LCGreen Plus	LS					5	SF3B1 mutation is a rare event in Chinese..	Yang	2013
SF3B1, SRSF2, DNMT3A, and U2AF35	Bone Marrow	FFPE	34	9			ResoLight	LC480 II						Tumor suppressor microRNAs are downregulated in..	Aslan,..	2016
SF3B3	Oral Cancer	F	78	25			ResoLight	LC480						Detection of SF3B3 Gene Mutations in Oral Cancer..	Chang	2014
SLC, POLR2A, ELF1, MRPL19	Pancreatic	F	32	17	61	120	None	ViiA7						The association between the expression of solute..	Mohelnikov..	2013
SLCO1B3	Tumor	FFPE	30	17	100	459	Resolight	LC480						SLCO1B3 screening in colorectal cancer patients..	Evangeli,..	2017
SMARCBI	rhabdoid tumor/blood sample	FFPE	60	9	195	313	EvaGreen	RG	100	14	93.3	14	9	Rapid detection of SMARCB1	Dager	2009
SPOP	Prostate Cancer	FFPE	720	2	102	123	ResoLight	LC480						SPOP Mutations in Prostate Cancer across..	Blattner	2014
SRSF2	Bone Marrow		249	1	212	212	LCGreen Plus	LS	90					The prognostic implication of SRSF2 mutations in..	Yang,..	2016
STMN1	Blood		54					Eco						Retrospective analysis of second-line..	Powrózek,..	2016
T85C	Gastric Cancer, Blood	F	112	1	91	91	EvaGreen	RG						T85C polymorphisms of the dihydropyrimidine..	Fang	2012
TGFRB2, HSP110, NR21, NR24, NR27, BAT25, BAT26	Colorectal Cancer	F	2	7	87	131	LCGreen Plus	LS						Enhanced detection of microsatellite instability..	Ladas,..	2018
TNF	Blood	F	761	1			EvaGreen	LC480						TNF-a 2308 G/A as a Risk Marker of Cervical..	Roszak,..	2015
TNFAIP3	Blood	F	131	13	215	340	ResoLight	LC480						Development of a high-resolution melting method..	Chang,..	2016
TNFRSF17	Colorectal cancer	F	297				EvaGreen	RG						The haplotypes of TNFRSF17 polymorphisms are..	Chae	2012
TP53	Liver	F	30	4	188	220	LCGreen Plus	LS						Genetic and epigenetic characteristics of human..	Taniguchi	2010
TP53	Lymphocytes	WB/cell lines	47	1			LCGreen Plus	LS						Determining the effectiveness of HRM analysis for..	Garritano	2009
TP53	Ovary	F	40	5	136	245	SYTO 9 (5 ÂµM)	RG	100	20	97.5	80	5	High resolution melting for mutation scanning of..	Krypuy	2007
TP53	Breast	F	40	5	136	245	SYTO 9 (5 ÂµM)	RG	100	7	100	93	5	High resolution melting for mutation scanning of..	Krypuy	2007
TP53	Breast	F	14	21	80	150	LCGreen Plus	LC480	100	7	98.6	287	0.5	High-throughput amplicon scanning of the TP53..	Bastien	2008
TP53	Breast	WGA	14	21	80	150	LCGreen Plus	LC480	86	7	92.7	287	0.5	High-throughput amplicon scanning of the TP53..	Bastien	2008
TP53	Breast	FFPE	14	21	80	150	LCGreen Plus	LC480	86	7	93.4	287	0.5	High-throughput amplicon scanning of the TP53..	Bastien	2008
TP53	Breast Tumor	cell line	47	22	134	653	LCGreen Plus (0.8x)	LS	86.1	166	83.1	763		Mutation and methylation analysis of the..	Gorringe	2008
TP53	Sarcoma, blood	FFPE	559	14	109	245	SYTO 9	LC480					3.6	High Frequency of Germline TP53 Mutations in a..	Mitchell	2013
TP53	Pancreas	F	180	4	148	267							.1	Mutant TP53 in Duodenal Samples of Pancreatic..	Kanda	2013
TP53	Colorectal Cancer	F, FFPE	24				LCGreen Plus	HR-96						Multiplex Amplification Coupled with COLD-PCR and..	Milbury	2011
TP53	Lung adenocarcinomas	F	9	2	111	129	LCGreen Plus	HR-96					3	COLD-PCR–Enhanced High-Resolution Melting..	Milbury	2009
TP53	Breast and Ovarian Cancer, Blood	F	28	21	80	150	SYTO 9							TP53 p.R337H prevalence in a series of Brazilian..	Cury	2014
TP53	Gastric cancer	F	14	14	109	245	SYTO 9	LC480						Role of p53 in the progression of gastric cancer	Busuttil	2014
TP53	Tumor	FFPE	45											A mutation screening of oncogenes, tumor..	Evangelist..	2015
TP53, EGFR, KRAS, PIK3CA and BRAF	Tumor	F	109				ResoLight	LC480						Epstein-Barr virus infection is strictly..	Doescher,..	2015
UGT1A16*	Blood		323	1	66	66	LCGreen Plus	LS96						Association between UGT1A1 Polymorphism and Risk..	Huangfu,..	2016
ureaseC, vacA, cagA, cagE and virB11	Tumor	F	119				Syto 9	7500 Fast						The intricate interplay between MSI and..	Silva-Fern..	2017
VHL, PPARG, PLCD1, RASSF1, BAP1, HYAL1, ACY1,..	Liver	F	32	193	125	275	EvaGreen	StepOnePlus						Mutations of candidate tumor suppressor genes at..	You,..	2017
WT1	Kidney	F	8				EvaGreen	RG						Bilateral Wilms Tumor and Early Presentation in..	Hu	2013
WT1	Bone	F	175	1			ResoLight	LC480	100	175	96.6	169		Analysis of SNP rs16754 of WT1 gene in a series..	Luna	2012
WTX	Nephroblastoma, Renal Tissue	Paraffin	8	4	138	341	ResoLight	LC480						Is predisposition for nephroblastoma linked to..	Guertl	2010
WWOX	Endometrium	F	79	1			SYBR Green I	RG						The WWOX tumor suppressor gene in endometrial..	Pluciennik	2013
XPV POLH	Skin Cancer						EvaGreen, SYBR Green I	CFX96						Xeroderma pigmentosum variant: Complementary..	Hentosh	2011
XRCC1	Blood	F	101	1				LC480						XRCC1 Gene Polymorphism, Clinicopathological..	Putthanach..	2015
XRCC1	Blood	F	303	1			Resolight	LC480						The XRCC 1 DNA repair gene modifies the..	Putthanach..	2017
XRCC1 and OGG1	Liver Cancer, blood	F	219	2				LC480						Gene–environment interaction involved in..	Songserm	2014
XRCC1 and RAD51	Blood, head and neck cancer	F	101	4			SYTO 9	RG						Association between single nucleotide..	Pratesi	2011
XRCC1 and XRCC3	Nasopharyngeal carcinoma, Blood		120											Association of XRCC1 and XRCC3 gene haplotypes..	Cheuk	2014
XRCC1, hMSH2, XPD, XRCC2, BRAC1, BRAC2	Blood	EDTA	1200	6			Resolight	LC 96						Data on Single Nucleotide Polymorphism of DNA..	Smolarz,..	2019
XRCC2	Thyroid		171	1	104	104		RG						Increased Risk of Differentiated Thyroid..	Fayaz	2013
XRCC2	Thyroid cancer	F	50	7	99	379	EvaGreen	RG						Assessment of genetic mutations in the XRCC2..	Fayaz	2012
XRCC3, BRCA1	Tumor	FFPE	190	1	74	74	LCGreen Plus	CFX384						High Resolution Melting (HRM) for High-Throughput..	S?omka,..	2017

Variant Scanning Of Human Tumors

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